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Bulletin of the National Research Centre

Table 4 Comparison of hematological, biochemical and anthropometric indicators among HIV-positive patients without treatment, HIV-positive patients on HAART, and people without HIV infection

From: Impact of highly active antiretroviral drug therapy (HAART) on biochemical, hematologic, atherogenic and anthropometric profiles of human immunodeficiency virus patients at a tertiary hospital in Owo, Nigeria

Paired indices

Group

HIV+ve

HAART

HIV−ve

r (p value)

r (p value)

r (p value)

WBC/L

0.24 (0.045)

0.01 (0.952)

0.08 (0.499)

N/L

− 0.61 (0.000)

− 0.61 (0.000)

− 0.68 (0.000)

N/CHOL

− 0.19 (0.111)

0.24 (0.047)

− 0.28 (0.019)

L/M

− 0.18 (0.134)

− 0.42 (0.000)

− 0.24 (0.046)

L/CHOL

0.05 (0.658)

− 0.06 (0.648)

0.24 (0.047)

CHOL/HDL-c

0.90 (0.000)

− 0.13 (0.288)

0.42 (0.000)

CHOL/LDL-c

0.39 (0.001)

0.04 (0.752)

0.70 (0.000)

TRIG/BMI

− 0.03 (0.780)

0.04 (0.715)

0.30 (0.011)

HDL-c/LDL-c

0.00 (0.972)

0.24 (0.041)

0.06 (0.630)

LDL-c/FPG

− 0.12 (0.311)

0.07 (0.550)

− 0.06 (0.601)

LDL-c/BMI

0.26 (0.031)

− 0.15 (0.214)

− 0.10 (0.404)

  1. The Pearson correlation coefficient, r, quantifies the degree to which paired indices are related. HIV infection and HAART in some instances caused significant deviations from the normal relationship between indices in healthy individuals
  2. HIV+ve HIV-positive patients, HAART HIV-positive patients on highly active antiretroviral therapy, HIV−ve HIV-negative subjects, WBC total white blood cell count, L lymphocyte count, CHOL total cholesterol concentration, M monocyte count, TRIG triglyceride concentration, HDL-c high-density lipoprotein-cholesterol concentration, LDL-c low-density lipoprotein-cholesterol concentration, BMI body mass index, FPG fasting plasma glucose, LDL low-density lipoprotein, HDL high-density lipoprotein
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