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Table 2 Comparison of Survival times (months) calculated using Kaplan–Meier analysis and the groups with the Log-rank test

From: Survival in patients with multiple myeloma: evaluation of possible associations with bone marrow fibrosis and investigation of factors independently associated with survival

  n Exitus Mean ± Standard Error (95% Confidence Interval) 5-year survival (%) p
Overall survival 72 24 81.54 ± 7.01 (67.80–95.29) 56.5 ± 7.4 N/A
Age      
 < 60 28 7 58.30 ± 5.45 (47.63–68.98) 56.4 ± 14.2 0.295
 ≥ 60 44 17 77.69 ± 8.80 (60.45–94.93) 55.1 ± 8.6  
Sex      
 Male 39 13 83.22 ± 9.17 (65.25–101.19) 59.0 ± 9.2 0.878
 Female 33 11 75.77 ± 10.42 (55.34–96.19) 52.0 ± 12.2  
Comorbidity      
 No 26 7 83.75 ± 12.80 (58.67–108.84) 54.2 ± 15.5 0.374
 Yes 46 17 71.59 ± 7.70 (56.49–86.69) 55.1 ± 8.5  
Type      
 Heavy chain 58 23 75.08 ± 7.72 (59.94–90.21) 50.4 ± 7.9 0.051
 Light chain 14 1 70.36 ± 4.47 (61.59–79.13) 92.9 ± 6.9  
Stage      
 Others 19 1 117.77 ± 6.95 (104.15–131.39) 92.3 ± 7.4 0.003
 Stage III (A/B) 47 22 62.21 ± 7.53 (47.46–76.96) 42.6 ± 8.8  
Lytic lesion      
 No 19 7 49.68 ± 7.80 (34.39–64.97) 58.3 ± 12.6 0.861
 Yes 33 16 52.19 ± 6.24 (39.96–64.42) 41.3 ± 10.2  
Plasmacytoma      
 No 48 16 79.97 ± 8.91 (62.50–97.44) 56.7 ± 8.9 0.683
 Yes 22 8 75.75 ± 10.32 (55.53–95.98) 53.8 ± 13.5  
Hypercalcemia      
 No 59 17 86.87 ± 7.65 (71.88–101.86) 62.3 ± 8.0 0.023
 Yes 9 6 32.94 ± 7.90 (17.46–48.43) 19.4 ± 16.2  
High creatinine (> 2)      
 No 53 14 89.86 ± 7.89 (74.39–105.33) 64.4 ± 8.5 0.012
 Yes 18 10 39.07 ± 7.18 (25.00–53.13) 28.7 ± 14.5  
Bone marrow fibrosis level      
 0 15 4 85.27 ± 11.77 (62.20–108.34) 70.9 ± 12.4 0.730
 1–4 55 18 82.66 ± 7.96 (67.07–98.26) 58.0 ± 8.3  
Response to treatment (primary line)      
 Others 25 12 48.45 ± 7.64 (33.47–63.43) 34.7 ± 13.6 0.003
 VGPR & CR 33 5 105.31 ± 7.92 (89.79–120.82) 78.5 ± 8.8  
Autologous stem cell transplantation      
 No 36 16 48.98 ± 6.90 (35.45–62.51) 42.2 ± 11.1 0.007
 Yes 35 7 99.64 ± 8.35 (83.28–116.01) 73.6 ± 8.8  
  1. p values marked with bold indicate statistically significant differences between the groups