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Table 1 The curative effect of methanol leaf extract of Piliostigma reticulatum against P. berghei in mice (n = 6)

From: In vivo antiplasmodial activity of the methanol leaf extract of Piliostigma reticulatum (Dc.) Hochst (Fabaceae)

Treatment (mg/kg) Mean % parasitemia Parasite clearance (%) Mean survival time (Days)
DW 10 ml/kg 82.72 ± 7.30 5.2 ± 1.17
MPR (250) 26.21 ± 1.67* 68.31 16.5 ± 1.38*
MPR (500) 19.42 ± 1.04* 76.53 17.3 ± 0.52*
MPR (1000) 13.52 ± 1.70* 83.65 18.8 ± 2.56*
Chloroquine (10) 9.02 ± 1.59* 89.09 26.2 ± 0.75*
Artesunate (5) 7.34 ± 1.69* 91.13 27.3 ± 0.52*
  1. Results are expressed as mean ± SEM. n = 6
  2. DW, distilled water; MPR, Piliostigma reticulatum methanol extract
  3. *Significantly different from control at P < 0.001 using One-way ANOVA and Dunnett’s post hoc test