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Bulletin of the National Research Centre

Table 1 The curative effect of methanol leaf extract of Piliostigma reticulatum against P. berghei in mice (n = 6)

From: In vivo antiplasmodial activity of the methanol leaf extract of Piliostigma reticulatum (Dc.) Hochst (Fabaceae)

Treatment (mg/kg)

Mean % parasitemia

Parasite clearance (%)

Mean survival time (Days)

DW 10 ml/kg

82.72 ± 7.30

–

5.2 ± 1.17

MPR (250)

26.21 ± 1.67*

68.31

16.5 ± 1.38*

MPR (500)

19.42 ± 1.04*

76.53

17.3 ± 0.52*

MPR (1000)

13.52 ± 1.70*

83.65

18.8 ± 2.56*

Chloroquine (10)

9.02 ± 1.59*

89.09

26.2 ± 0.75*

Artesunate (5)

7.34 ± 1.69*

91.13

27.3 ± 0.52*

  1. Results are expressed as mean ± SEM. n = 6
  2. DW, distilled water; MPR, Piliostigma reticulatum methanol extract
  3. *Significantly different from control at P < 0.001 using One-way ANOVA and Dunnett’s post hoc test
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