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Bulletin of the National Research Centre

Table 7 Effect of Ipomoea asarifolia ethanolic leaf extract on 4-aminopyridine-induced seizures in mice

From: Anti-seizure properties of Ipomoea asarifolia (Desr.) (Convolvulaceae) ethanolic leaf extract in laboratory animals

Treatment (mg/kg)

Onset of seizures (Min.)

Quantal protection

Percentage protection

D/W 10 mL/kg

8.33 ± 0.56

0/6

0.00

IALE 150

14.00 ± 0.91*

0/6

0.00

IALE 300

16.50 ± 1.15**

0/6

0.00

IALE 600

18.33 ± 1.17**

0/6

0.00

PHB 10

–

6/6

100.00

  1. Data are presented as Mean ± S.E.M., * = p < 0.01, ** = p < 0.001 as compared to D/W group—One-way ANOVA followed by Dunnett’s post hoc test, n = 6, compared to D/W group, D/W = Distilled water, IALE = Ipomoea asarifolia leaf extract, PHB = Phenobarbitone
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