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Table 4 Protective effect of coconut water on lipid profiles of carbon tetrachloride-induced toxicity in male (A) and female (B) rats

From: Protective effects of coconut water against the intraperitoneal infused carbon tetrachloride-induced toxicity—evaluations of biochemical, haematological and histopathological profiles in rats

Parameters

Control

CCl4 only

Coconut water (mL/kg)

2 mL/kg

4 mL/kg

6 mL/kg

A

     

TC (mg/dL)

133.57 ± 4.04a

152.57 ± 2.65b

144.20 ± 2.13c

142.83 ± 1.96c

135.47 ± 2.12a

HDL-C (mg/dL)

76.83 ± 1.21a

65.43 ± 1.70b

68.10 ± 3.35b

72.47 ± 2.60c

73.80 ± 3.35c

Triglycerides (mg/dL)

155.00 ± 6.85a

179.47 ± 3.05b

170.50 ± 1.08c

172.43 ± 2.90c

167.97 ± 2.62c

LDL-C (mg/dL)

25.73 ± 3.41a

45.24 ± 35.89b

42.19 ± 5.13b

36.55 ± 3.58c

28.07 ± 5.36a

VLDL-C (mg/dL)

31.00 ± 1.37a

35.89 ± 0.61a

34.10 ± 0.22a

33.82 ± 0.70a

33.59 ± 0.52a

B

     

TC (mg/dL)

142.20 ± 4.40a

149.80 ± 5.70b

144.20 ± 2.80a

144.20 ± 2.20a

142.30 ± 3.40a

HDL-C (mg/dL)

77.20 ± 2.10a

67.80 ± 1.80b

70.90 ± 2.20c

72.90 ± 2.00c

73.70 ± 2.90c

Triglycerides (mg/dL)

171.70 ± 4.50a

186.80 ± 4.10b

178.00 ± 2.50c

178.20 ± 2.20c

178.70 ± 2.30c

LDL-C (mg/dL)

30.70 ± 3.20a

45.30 ± 3.80b

37.70 ± 2.80c

35.50 ± 1.60c

32.90 ± 1.90a

VLDL-C (mg/dL)

34.30 ± 1.80a

37.30 ± 1.84b

35.60 ± 1.50c

35.60 ± 1.40c

35.70 ± 1.90c

  1. TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; and VLDL-C, very low-density lipoprotein cholesterol. Values in the row bearing the same letters of the alphabet are not statistically significant (p > 0.05) from one another. The data were analysed with one-way ANOVA and expressed as mean ± SD, then compared to controls, n = 6. Different letters (a, b or c) p < 0.05 both male and female rats show significant difference between the tested groups (2, 4 and 6 mL/kg) compared to the negative control