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Table 1 Protective effect of coconut water on liver biomarkers of carbon tetrachloride-induced toxicity in male (A) and female (B) rats

From: Protective effects of coconut water against the intraperitoneal infused carbon tetrachloride-induced toxicity—evaluations of biochemical, haematological and histopathological profiles in rats

Parameters

Control

CCl4 only

Coconut water (mL/kg)

2 mL/kg

4 mL/kg

6 mL/kg

A

     

Total protein (g/dl)

7.20 ± 0.07a

5.65 ± 0.11b

5.79 ± 0.09b

6.03 ± 0.25c

6.12 ± 0.15a

Albumin (g/dl)

4.22 ± 0.04a

3.37 ± 0.20b

3.36 ± 0.43b

3.40 ± 0.37b

3.34 ± 0.56b

AST (U/L)

18.67 ± 3.06a

80.33 ± 2.52b

74.67 ± 4.16c

71.67 ± 0.58c

70.67 ± 3.06c

ALT (U/L)

10.33 ± 1.53a

74.67 ± 4.16b

64.67 ± 0.58c

63.00 ± 1.00c

63.00 ± 2.65c

ALP (U/L)

58.70 ± 3.87a

71.67 ± 0.58b

72.83 ± 1.19b

72.97 ± 0.50b

71.97 ± 1.39b

Bilirubin (g/dl)

0.50 ± 0.08a

1.65 ± 0.10b

1.41 ± 0.09c

1.31 ± 0.09c

1.27 ± 0.04c

B

     

Total protein (g/dl)

6.56 ± 0.40a

5.16 ± 0.22b

5.83 ± 0.04c

5.46 ± 0.66d

5.57 ± 0.33c

Albumin (g/dl)

4.13 ± 0.29b

2.91 ± 0.25a

3.09 ± 0.06c

2.97 ± 0.13a

3.05 ± 0.07c

AST (U/L)

22.33 ± 2.52b

87.67 ± 1.53a

80.00 ± 2.00c

79.67 ± 4.73c

70.00 ± 2.00d

ALT (U/L)

12.00 ± 2.00a

78.67 ± 3.51b

65.67 ± 6.03c

61.33 ± 1.15c

60.00 ± 2.00c

ALP (U/L)

58.57 ± 4.30a

81.37 ± 3.81b

71.33 ± 1.12c

72.23 ± 1.72c

72.10 ± 2.33c

Bilirubin (g/dl)

0.45 ± 0.06a

1.60 ± 0.25b

1.06 ± 0.23c

1.07 ± 0.29c

0.98 ± 0.10c

  1. AST, aspartate aminotransferase; ALT, alanine transaminase; and ALP, alkaline phosphatase. Values are presented as mean ± SD, n = 6. Values in the row bearing the same letters of the alphabet are not statistically significant (p > 0.05) from one another. The data were analysed with one-way ANOVA and expressed as mean ± SD, then compared to controls, n = 6. Different letters (a, b or c) p < 0.05 both male and female rats show significant difference between the tested groups (2, 4 and 6 mL/kg) compared to the negative control