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Table 2 Effect of C. albidum and I. gabonensis extracts on GSH, MDA levels and glutathione GPx activities of rat liver and heart homogenates

From: Methanol leaf extracts of Chrysophyllum albidum and Irvingia gabonensis protected against dyslipidaemia and oxidative stress induced by high-fat diet in Wistar rats

 

GSH (µg/ml)

GPx (mgGSH oxid./min/g tissue)

MDA (mM/g tissue)

 

Liver

Heart

Liver

Heart

Liver

Heart

NFD control

83.20 ± 3.05a

28.88 ± 4.13a

20.88 ± 0.25a

18.69 ± 0.31a

1.10 ± 0.22a

0.74 ± 0.01a

HFD control

49.23 ± 3.98 b

4.69 ± 1.19b

15.75 ± 0.25b

13.63 ± 0.25b

2.94 ± 0.06b

1.08 ± 0.02b

HFD + C. albidum 250 mg/kg

72.63 ± 2.63a

5.13 ± 0.63b

19.08 ± 0.45a

20.76 ± 0.63a

1.42 ± 0.09ac

0.75 ± 0.22ac

HFD + C. albidum 500 mg/kg

73.32 ± 5.19a

22.5 ± 2.75a

20.82 ± 0.57a

19.32 ± 0.63a

2.20 ± 0.14d

0.88 ± 0.04c

HFD + I. gabonensis 250 mg/kg

71.57 ± 3.69a

3.63 ± 0.13b

20.76 ± 0.88a

19.32 ± 0.94a

2.10 ± 0.10 d

0.87 ± 0.08c

HFD + I. gabonensis 500 mg/kg

80.51 ± 1.74a

9.63 ± 1.13b

20.63 ± 0.50a

18.88 ± 0.50a

2.18 ± 0.11d

0.88 ± 0.03c

  1. a, b, c, d These lower case letters a, b, c and d are different levels of significance at p < 0.05. a is significantly different from b and c, and vice versa. b is also significantly different from c and vice versa. The use of such alphabets is to show the homogenous sets which would bear same alphabet so that the different sets can easily be identified
  2. Data are expressed as mean ± SEM (n = 6). Values in the same column with different superscripts are significantly different (p < 0.05) from each other