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Table 3 ProToxII server toxicology profile of the lead and standard compounds

From: Computational evaluation of bioactive compounds from Vitis vinifera as a novel β-catenin inhibitor for cancer treatment

Compound

Predicted LD50 (mg/kg)

Predicted toxicity class

Carcinogenicity

Hepatotoxicity

Cis-astringin

1380

4

 − 

 − 

Rutin

5000

5

 − 

 − 

Caftaric acid

3800

5

 − 

 − 

Trans-caftaric acid

3800

5

 − 

 − 

Procyanidin B3

2500

5

 − 

 − 

Cis-Miyabenol C

500

4

 − 

 − 

Ampelopsin H

500

4

 − 

 − 

Leucovorin

135

3

 − 

 − 

Calcium xeloda

1000

4

 − 

 +