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Table 8 RMSD (Ã…) values and total free energy after energy minimization of both wild-type and mutated protein models

From: Computational analysis uncovers the deleterious SNPs along with the mutational spectrum of p53 gene and its differential expression pattern in pan-cancer

Mutated models

Energy after minimization (kj/mol)

RMSD (Ã…)

Wild Type

− 161,568.4

 

S241F

− 157,568.4

4.32

R248Q

− 159,349.4

4.27

R248W

− 158,244.0

3.74

R273H

− 156,160.6

4.68

R273C

− 155,923.0

3.60