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Table 6 Functional domains and their position in p53 protein

From: Computational analysis uncovers the deleterious SNPs along with the mutational spectrum of p53 gene and its differential expression pattern in pan-cancer

Amino acid position in the protein

Domain name

5–29

p53 transactivation domain (p53_TAD)

95–288

p53 DNA binding domain

319–357

p53 tetramerization domain