Table 4 Summary of amino acids (conservation profile) in that corresponds to region with high-risk nsSNPs. CS: conservation score, color (6–9 = conserved, 5 = average and 1–4 = variable); (s): predicted structural site; (f): predicted functional site
Residue position | Amino acid | CS | Color | B/E | function |
|---|---|---|---|---|---|
110 | R | 1.057 | 1 | E | S |
133 | M | − 1.019 | 9 | B | S |
151 | P | − 0.801 | 8 | E | F |
175 | R | − 0.989 | 9 | E | F |
241 | S | − 1.162 | 9 | E | F |
248 | R | − -1.070 | 9 | E | F |
249 | R | − 0.990 | 9 | E | F |
257 | L | − 0.951 | 9 | B | S |
267 | R | − 0.944 | 9 | E | F |
273 | R | − 1.073 | 9 | E | F |
278 | P | − 1.030 | 9 | E | F |
282 | R | − 1.029 | 9 | E | F |
285 | E | − 0.878 | 8 | E | F |