Neonatal orally administered curcumin: impact on the metabolic response and renal histology of Sprague-Dawley rats fed a high-fructose diet until adolescence

Bulletin of the National Research Centre

Table 4 High-fructose diet impact on lipid biomarkers at post-natal day 63 in male and female rats administered curcumin during suckling

^{a, b}Means across columns (in males and females) with similar superscripts are similar (p > 0.05) using one-way ANOVA across all eight groups for the plasma concentration of triglycerides and cholesterol. TG, triglyceride. DMSO + TW = 10 ml kg⁻¹ of a 0.5% dimethyl sulphoxide solution as neonates and plain tap water post-weaning, DMSO + FW = 10 ml kg⁻¹ of a 0.5% dimethyl sulphoxide solution as neonates and fructose (20%, w/v) as drinking fluid in the growing period, CC + TW = curcumin (500 mg kg⁻¹ in 0.5% DMSO) as neonates and plain tap water in the growing period, CC + FW = curcumin (500 mg kg⁻¹ in 0.5% DMSO) as neonates and fructose (20%, w/v) as drinking fluid in the growing period, FW + TW = fructose (20%, w/v) as neonates and plain tap water in the growing period, FW + FW = fructose (20%, w/v) as neonates and fructose (20%, w/v) as drinking fluid in the growing period, CCFW + TW = curcumin (500 mg kg⁻¹) and fructose (20%, w/v) in 0.5% DMSO as neonates and plain tap water in the growing period, CCFW + FW = curcumin (500 mg kg⁻¹) and fructose (20%, w/v) in 0.5% DMSO as neonates and fructose (20%, w/v) in the growing period. Data expressed as mean ± SEM, n = 7–9 per group