Fig. 3

Kidney histology (MT staining) of representative adolescent a male and b female rats administered curcumin during suckling. The black arrows point to mild-to-moderate tubular secretions, while the green arrows point to mesangial proliferation. DMSO + TW = 10 ml kg⁻¹ of a 0.5% dimethyl sulphoxide solution as neonates and plain tap water post-weaning, DMSO + FW = 10 ml kg⁻¹ of a 0.5% dimethyl sulphoxide solution as neonates and fructose (20%, w/v) as drinking fluid in the growing period, CC + TW = curcumin (500 mg kg⁻¹ in 0.5% DMSO) as neonates and plain tap water in the growing period, CC + FW = curcumin (500 mg kg⁻¹ in 0.5% DMSO) as neonates and fructose (20%, w/v) as drinking fluid in the growing period, FW + TW = fructose (20%, w/v) as neonates and plain tap water in the growing period, FW + FW = fructose (20%, w/v) as neonates and fructose (20%, w/v) as drinking fluid in the growing period, CCFW + TW = curcumin (500 mg kg⁻¹) and fructose (20%, w/v) in 0.5% DMSO as neonates and plain tap water in the growing period, CCFW + FW = curcumin (500 mg kg⁻¹) and fructose (20%, w/v) in 0.5% DMSO as neonates and fructose (20%, w/v) in the growing period. Scale bar in DMSO + TW = 100 µm applies to all the figures