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Table 7 Result of checkpoint batches

From: Formulation and optimization of polymeric agglomerates of Bosentan monohydrate by crystallo-co-agglomeration technique

Batches

Talc (mg)

PEG6000 (mg)

Speed (RPM)

Particle size (µm) (Y1)

Angle of repose (Y2)

Drug content % (Y3)

Predicted

Actual

Predicted

Actual

Predicted

Actual

BOS 14

0.88

2.75

700

9.36

10.87 ± 0.46

32.87°

31 ± 0.15°

73

75.81 ± 0.31

BOS 15

1.63

4.25

900

8.65

9.32 ± 0.59

33.46°

35.2 ± 0.11°

66.59

68.16 ± 0.15

  1. Mean ± SD = 3, n = 3