Table 6 Results of Box–Behnken designs
Batch | Talc (%) | PEG 6000(%) | SPEED (RPM) | Y1 (particle size) µm | Y2 (angle of repose) degree | Y3 (drug content) % | ||
|---|---|---|---|---|---|---|---|---|
BOS 1 | 2.00 | 3.50 | 1000 | 06.45 ± 0.028 | 36.33 ± 0.473 | 64.28 ± 0.509 | ||
BOS 2 | 2.00 | 5.00 | 800 | 09.56 ± 2.107 | 32.67 ± 0.233 | 74.55 ± 0.318 | ||
BOS 3 | 2.00 | 3.50 | 600 | 09.86 ± 0.098 | 32.88 ± 0.848 | 89.73 ± 0.190 | ||
BOS 4 | 0.50 | 2.00 | 800 | 06.10 ± 0.212 | 35.33 ± 0.473 | 62.05 ± 0.671 | ||
BOS 5 | 1.25 | 5.00 | 600 | 13.57 ± 0.219 | 30.00 ± 0.707 | 93.89 ± 0.077 | ||
BOS 6 | 0.50 | 5.00 | 800 | 06.24 ± 0.077 | 36.67 ± 0.233 | 68.3 ± 0.494 | ||
BOS 7 | 0.50 | 3.50 | 1000 | 05.95 ± 0.035 | 37.67 ± 0.233 | 51.78 ± 0.466 | ||
BOS 8 | 0.50 | 3.50 | 600 | 07.26 ± 0.169 | 34.33 ± 0.473 | 68.3 ± 0.486 | ||
BOS 9 | 1.25 | 2.00 | 600 | 12.67 ± 0.233 | 31.00 ± 0.707 | 85.34 ± 0.601 | ||
BOS 10 | 2.00 | 2.00 | 800 | 07.15 ± 0.176 | 34.67 ± 0.233 | 85.34 ± 0.311 | ||
BOS 11 | 1.25 | 2.00 | 1000 | 06.79 ± 0.148 | 36.95 ± 0.035 | 69.15 ± 0.622 | ||
BOS 12 | 1.25 | 3.50 | 800 | 09.15 ± 0.247 | 32.33 ± 0.473 | 72.56 ± 0.155 | ||
BOS 13 | 1.25 | 3.50 | 1000 | 07.176 ± 0.087 | 34 ± 0.707 | 51.12 ± 0.494 | ||