Table 2 Summary of the effects of d-pinitol on patients with diabetes mellitus
From: Effects of d-pinitol on diabetes mellitus: an updated review
S.No. | Author | Year | Dose applied | Major mechanism/effect |
|---|---|---|---|---|
1. | Kim et al., | 2012 | 1200 mg/day for 12 weeks | Significant reduction in HbA1C, fasting plasma glucose and HOMA-IR |
2. | Kang et al., | 2006 | 1.2 g/day for 12 weeks | Marked reduction in post-prandial blood glucose levels |
3. | Kim et al., | 2005 | 600 mg/day for 12 weeks | Significant reduction in plasma glucose, insulin, fructosamine, HbA1C, HOMA-IR, LDL cholesterol, LDL/HDL cholesterol ratio, triglycerides, TG/Cholesterol ratio and a significant (P < 0.05) increase in HDL cholesterol |
4. | Kim et al., | 2007 | 20 mg/kg/day for 12 weeks | Fasting glucose, post-prandial glucose levels and hemoglobin A1c were significantly decreased |
5. | Davis et al., | 2000 | 20 mg/kg/day for 28 days | No significant changes in the plasma glucose and insulin levels |