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Table 1 Comparison between the different studied groups according to different ECG parameters

From: A comparative study of the cardioprotective effect of Metformin, Sitagliptin and Dapagliflozin on Isoprenaline induced myocardial infarction in non-diabetic rats

 

Normal control

ISO induced MI

Metformin

Sitagliptin

Dapagliflozin

F

p

R-R (s)

0.27 ± 0.02

0.22* ± 0.01

0.24*# ± 0.01

0.25# ± 0.02

0.28#$& ± 0.01

19.029*

≤ 0.05

HR (bpm)

247.4 ± 31.68

287.7* ± 16.72

256.0# ± 13.98

236.5# ± 23.22

223.4#$ ± 10.15

13.858*

≤ 0.05

QT (s)

0.043 ± 0.008

0.095* ± 0.005

0.074*# ± 0.006

0.063*#$ ± 0.007

0.050#$& ± 0.007

96.537*

≤ 0.05

R (mv)

528.8 ± 51.39

308.4* ± 7.86

376.1*# ± 22.86

465.6*#$ ± 76.63

490.0#$ ± 54.8

33.304*

≤ 0.05

ST (mv)

94.74 ± 29.19

131.0* ± 13.09

100.6# ± 9.03

94.53#$ ± 16.12

44.23*#& ± 27.09

23.168*

≤ 0.05

  1. F: F for ANOVA test, Pairwise comparison bet. Each 2 groups was done using Post Hoc Test, (Tukey)
  2. *Statistically significant at p ≤ 0.05, *: Significant between C-ve and each other group
  3. #Significant between C + ve and each other group, $: Significant between Metformin and each other group
  4. &Significant between Sitagliptin and Dapagliflozin