Fig. 1

Submucosal fibroadipose tissue almost entirely effaced by multiple empty spaces and large pools of pale staining eosinophilic material (A) eliciting a prominent foreign-body giant cell granulomatous response (B). Non-necrotizing granulomatous inflammation with numerous multinucleated foreign-body giant cells (C, arrowed) surround the pale pink stained material (D) (H&E stain; original magnification × 200 (A, B). × 400 (C, D)