Skip to main content

Table 5 Binding Energy results of the synthesized triphenylamine chalcones with target receptor (PDB: 5VBU)

From: Design, synthesis, docking studies and antibiotic evaluation (in vitro) of some novel (E)-4-(3-(diphenylamino)phenyl)-1-(4-methoxyphenyl)-2-methylbut-3-en-1-one and their analogues

Triphenylamine chalcones Binding energy (kcal/mol)
1a  − 10.1
1b  − 10.7
1c  − 10.4
1d  − 9.4
2a  − 11.2
2b  − 10.7
2c  − 10.3
2d  − 10.3
Fluconazole  − 7.9
Cifroplaxacin  − 7.3