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Table 4 Minimum Bactericidal/Fungicidal Concentrations (MBC/MFC) (µg/ml) of the synthesized triphenylamine chalcones against the test microbes

From: Design, synthesis, docking studies and antibiotic evaluation (in vitro) of some novel (E)-4-(3-(diphenylamino)phenyl)-1-(4-methoxyphenyl)-2-methylbut-3-en-1-one and their analogues

Test Organisms

Triphenylamine chalcones

1a

1b

1c

1d

2a

2b

2c

2d

E. coli

–

–

–

50

–

100

100

–

P. aeruginosa

–

100

100

100

–

100

50

100

S. typhi

–

–

100

–

–

–

–

100

S. aureus

–

–

–

100

–

–

–

–

B. subtilis

–

100

100

50

100

50

50

100

MRSA

–

–

100

100

–

100

–

100

C. albicans

100

100

50

100

100

50

50

100

A. niger

50

50

50

50

50

50

50

50

  1. Key; (–): No MBC/MFC