Table 4 Estimated minimum free energy (MFE) of miRNAs second structures using RNAfold
SNP | miRNA | Inclusion in mature miRNA | MFE in the presence of ancestral allele (kcal/mol) | MFE in the presence of variant allele (kcal/mol) |
|---|---|---|---|---|
rs530404895 | miRNA-326 | – | − 54.70 | − 42.60 |
rs374732351 | miRNA-326 | – | − 54.70 | − 38.40 |
rs753764536 | miRNA-326 | – | − 54 to 70 | − 39.00 |
rs143525573 | miRNA-125A | – | − 44.74 | − 45.50 |
rs34059726 | miRNA-124-3 | – | − 41.93 | − 41.93 |