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Table 5 Threshold inhibitory concentration (IC50) of crude aqueous and methanolic extracts of leaves, stem and roots of C. dependens and ascorbic acid standard on nitric oxide radicals

From: Antiplasmodial and in vitro antioxidant potentials of crude aqueous and methanol extracts of Chasmanthera dependens (Hochst)

Extracts Threshold inhibitory concentration (*IC50) Mathematical model Equation R2
CDRM 1.16 ± 0.12 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.95
CDLM 1.10 ± 0.11 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.94
CDSM 1.25 ± 0.26 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.89
CDRA 1.32 ± 0.14 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.95
CDLA 1.62 ± 0.24 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.94
CDSA 1.36 ± 0.22 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.92
AA 0.65 ± 0.07 Sigmoid (a, b, c) \(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\) 0.91
  1. CDRM, C. dependens root methanol; CDLM, C. dependens leaves methanol; CDSM, C. dependens stem methanol; CDRA, C. dependens root aqueous; CDLA, C. dependens leaves aqueous; CDSA, C. dependens stem aqueous; AA, ascorbic acid
  2. *IC50 is the concentration of extract or standard that scavenged 50% of the generated free radicals