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Table 5 Threshold inhibitory concentration (IC50) of crude aqueous and methanolic extracts of leaves, stem and roots of C. dependens and ascorbic acid standard on nitric oxide radicals

From: Antiplasmodial and in vitro antioxidant potentials of crude aqueous and methanol extracts of Chasmanthera dependens (Hochst)

Extracts

Threshold inhibitory concentration (*IC50)

Mathematical model

Equation

R2

CDRM

1.16 ± 0.12

Sigmoid (a, b, c)

\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)

0.95

CDLM

1.10 ± 0.11

Sigmoid (a, b, c)

\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)

0.94

CDSM

1.25 ± 0.26

Sigmoid (a, b, c)

\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)

0.89

CDRA

1.32 ± 0.14

Sigmoid (a, b, c)

\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)

0.95

CDLA

1.62 ± 0.24

Sigmoid (a, b, c)

\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)

0.94

CDSA

1.36 ± 0.22

Sigmoid (a, b, c)

\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)

0.92

AA

0.65 ± 0.07

Sigmoid (a, b, c)

\(y=\frac{a}{1 +\mathrm{exp}\left(-\left(\frac{x-{x}_{0}}{b}\right)\right)}\)

0.91

  1. CDRM, C. dependens root methanol; CDLM, C. dependens leaves methanol; CDSM, C. dependens stem methanol; CDRA, C. dependens root aqueous; CDLA, C. dependens leaves aqueous; CDSA, C. dependens stem aqueous; AA, ascorbic acid
  2. *IC50 is the concentration of extract or standard that scavenged 50% of the generated free radicals