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Table 5 Toxicity profile of citral

From: Essential oil from Cymbopogon citratus exhibits “anti-aspergillosis” potential: in-silico molecular docking and in vitro studies

Classification

Target

Prediction

Toxicity end points

Carcinogenicity

Inactive

Toxicity end points

Mutagenicity

Inactive

Toxicity end points

Cytotoxicity

Inactive

Tox21-nuclear receptor signalling pathways

Aryl hydrocarbon Receptor (AhR)

Inactive

Tox21-nuclear receptor signalling pathways

Androgen Receptor (AR)

Inactive

Tox21-nuclear receptor signalling pathways

Androgen Receptor Ligand Binding Domain (AR-LBD)

Inactive

Tox21-nuclear receptor signalling pathways

Peroxisome Proliferator Activated Receptor Gamma (PPAR-Gamma)

Inactive

Tox21-stress response pathways

Nuclear factor (erythroid-derived 2)-like 2/antioxidant responsive element (nrf2/ARE)

Inactive

Tox21-stress response pathways

Heat shock factor response element (HSE)

Inactive

Tox21-stress response pathways

Mitochondrial Membrane Potential (MMP)

Inactive

Tox21-stress response pathways

Phosphoprotein (Tumor Supressor) p53

Inactive

Tox21-stress response pathways

ATPase family AAA domain-containing protein 5 (ATAD5)

Inactive