In-silico activity prediction, structure-based drug design, molecular docking and pharmacokinetic studies of selected quinazoline derivatives for their antiproliferative activity against triple negative breast cancer (MDA-MB231) cell line

Bulletin of the National Research Centre

Table 4 Result of Y-randomization test of the selected model

Model	R	R²	Q²
Original	0.935611	0.875367	0.472886
Random 1	0.673207	0.453208	− 0.49528
Random 2	0.339829	0.115484	− 1.11468
Random 3	0.494563	0.244592	− 0.21047
Random 4	0.450413	0.202872	− 0.85992
Random 5	0.556608	0.309812	− 1.14735
Random 6	0.5238	0.274366	− 0.46273
Random 7	0.551894	0.304587	− 0.41126
Random 8	0.293835	0.086339	− 0.72515
Random 9	0.529202	0.280055	− 1.12015
Random 10	0.567466	0.322018	− 0.36167