Palm oil extracts protected against cadmium chloride poisoning via inhibition of oxidative stress in rats

Ichipi-Ifukor, Patrick Chukwuyenum; Asagba, Samuel Ogheneovo; Nwose, Chibueze; Mordi, Joseph Chukwufumnanya; Oyem, John Chukwuma

doi:10.1186/s42269-021-00688-7

Bulletin of the National Research Centre

Table 1 Effect of palm oil fractions on levels of malondialdehyde (MDA) in tissue and serum of rats administered cadmium (μmol ml⁻¹)

From: Palm oil extracts protected against cadmium chloride poisoning via inhibition of oxidative stress in rats

Tissues	Experimental groups
Tissues	1	2	3	4	5	6
Twelve hours
Liver	0.59 ± 0.03^a	1.33 ± 0.12^b	1.21 ± 0.18^bd	0.87 ± 0.02^c	1.24 ± 0.04^bd	1.08 ± 0.10^cd
Kidney	0.70 ± 0.08^a	1.27 ± 0.02^b	0.94 ± 0.19^ab	0.89 ± 0.12^a	0.95 ± 0.22^ab	0.96 ± 0.14^ab
Heart	0.54 ± 0.27^a	1.34 ± 0.22^b	1.12 ± 0.08^b	0.77 ± 0.11^a	1.04 ± 0.04^b	1.14 ± 0.09^b
Brain	0.44 ± 0.15	0.48 ± 0.10	0.51 ± 0.11	0.47 ± 0.08	0.51 ± 0.19	0.39 ± 0.24
Muscle	0.63 ± 0.06^a	0.83 ± 0.12^ab	0.81 ± 0.15^ab	0.84 ± 0.09^ab	0.78 ± 0.08^ab	0.87 ± 0.07^b
Serum	0.56 ± 0.05^a	0.92 ± 0.05^b	0.73 ± 0.11^c	0.82 ± 0.06^b	0.71 ± 0.03^c	0.82 ± 0.06^b
Twenty four hours
Liver	0.85 ± 0.09^a	2.72 ± 0.15^b	1.55 ± 0.17^c	1.40 ± 0.39^c	1.76 ± 0.13^c	1.12 ± 0.06^ac
Kidney	0.82 ± 0.11^a	2.85 ± 0.11^b	1.17 ± 0.32^a	1.08 ± 0.20^a	1.00 ± 0.13^a	1.04 ± 0.16^a
Heart	0.54 ± 0.13^a	2.71 ± 0.22^b	1.40 ± 0.16^c	1.41 ± 0.18^c	1.50 ± 0.16^c	1.66 ± 0.09^c
Brain	0.49 ± 0.07	0.58 ± 0.19	0.64 ± 0.14	0.69 ± 1.00	0.46 ± 0.23	0.46 ± 0.29
Muscle	0.49 ± 0.05^a	0.71 ± 0.12^ab	0.68 ± 0.09^ab	0.82 ± 0.08^b	0.53 ± 0.09^a	0.61 ± 0.06^bc
Serum	0.63 ± 0.10^a	1.52 ± 0.84^b	0.83 ± 0.25^ac	0.76 ± 0.04^ac	0.99 ± 0.07^c	0.86 ± 0.17^ac
Forty eight hours
Liver	0.70 ± 1.07^a	2.87 ± 0.16^b	1.69 ± 0.81^c	1.34 ± 0.18^d	1.91 ± 0.11^c	1.69 ± 0.08^c
Kidney	0.72 ± 0.08^a	2.80 ± 0.11^b	1.45 ± 0.17^c	1.35 ± 0.22^c	1.76 ± 0.06^d	1.18 ± 0.67^c
Heart	0.54 ± 0.06^a	2.67 ± 0.17^b	1.46 ± 0.16^c	1.51 ± 0.09^c	1.46 ± 0.09^c	1.70 ± 0.14^c
Brain	0.43 ± 0.03^a	0.93 ± 0.08^b	0.66 ± 0.03^c	0.75 ± 0.08^c	0.53 ± 0.08^c	0.63 ± 0.07^c
Muscle	0.51 ± 0.05^a	0.83 ± 0.05^b	0.73 ± 0.07^b	0.79 ± 0.06^b	0.51 ± 0.05^a	0.55 ± 0.07^a
Serum	0.64 ± 0.06^a	1.57 ± 0.06^b	0.78 ± 0.07^a	0.88 ± 0.07^ad	0.99 ± 0.09^c	0.96 ± 0.07^cd

All values are expressed as Mean ± SD, values sharing different alphabet superscript on the same row showed a significant difference
Key: 1 = Control, 2 = CdCl₂, 3 = CF + CdCl_2, 4 = GF + CdCl₂, 5 = BF + CdCl_2, 6 = UF + CdCl₂

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