Bulletin of the National Research Centre

Table 4 Kidney parameters of rats following 28-day repeated administration of Culcasia angolensis leaves extract (CAE)

From: Preliminary sub-acute toxicological assessment of methanol leaves extract of Culcasia angolensis (Araceae) in Wistar rats

Parameters	Treatment group (mg/kg)
Parameters	DW (1 ml/kg)	CAE (125)	CAE (250)	CAE (500)
Urea (mmol/L)	32.2 ± 1.22	30.80 ± 0.89	31.66 ± 2.70	38.40 ± 1.82*
Creatinine (mmol/L)	0.80 ± 0.05	0.85 ± 0.11	0.88 ± 0.12	0.90 ± 0.60
Sodium (mmol/L)	220.32 ± 7.44	221.56 ± 2.99	225.08 ± 6.91	222.98 ± 3.24
Potassium (mmol/L)	7.90 ± 0.10	6.76 ± 1.20	7.30 ± 0.36	6.60 ± 2.27
Chloride (mmol/L)	96.67 ± 5.39	98.67 ± 5.26	87.83 ± 3.02	89.40 ± 1.50
Bicarbonate (mmol/L)	88.8 ± 3.30	88.60 ± 2.11	94.50 ± 3.71	89.84 ± 1.82

The values were tabulated as mean ± SEM; *p ≤ 0.05 compared to control group (one-way ANOVA followed by Dunnett's post hoc test), n = 6
DW distilled water, CAE Culcasia angolensis leaves extract

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