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Table 2 Haematological parameters of rats following 28-day repeated administration of Culcasia angolensis leaves extract (CAE)

From: Preliminary sub-acute toxicological assessment of methanol leaves extract of Culcasia angolensis (Araceae) in Wistar rats

Parameters Treatment (mg/kg)
DW (1 ml/kg) CAE (125) CAE (250) CAE (500)
WBC (× 109/L) 3.85 ± 0.27 4.07 ± 0.22 4.27 ± 0.10 3.85 ± 0.15
HGB (g/dL) 12.72 ± 0.33 12.62 ± 0.97 11.15 ± 0.69 11.12 ± 0.51
RBC (× 106/µL) 5.85 ± 0.17 5.98 ± 0.15 5.70 ± 0.14 5.93 ± 0.19
PLT (× 103/µL) 7.20 ± 0.10 7.18 ± 0.10 7.18 ± 0.11 7.08 ± 0.06
HCT (%) 37.16 ± 1.86 36.67 ± 3.18 35.00 ± 1.97 35.17 ± 1.30
MON (%) 2.33 ± 0.56 1.67 ± 0.21 1.50 ± 0.34 2.00 ± 0.37
LYMPH (%) 78.17 ± 1.17 77.67 ± 0.72 78.50 ± 0.99 81.33 ± 1.38*
ENP (%) 2.17 ± 0.30 1.66 ± 0.33 2.00 ± 0.36 1.83 ± 0.31
NTP (%) 17.33 ± 2.08 19.00 ± 0.97 18.00 ± 1.15 15.00 ± 0.97
  1. The values were tabulated as mean ± SEM, *p ≤ 0.05 in relation to the control group (one-way ANOVA followed by Dunnett’s post hoc test), n = 6
  2. DW distilled water, CAE Culcasia angolensis leaves extract, WBC white blood cell, RBC red blood cells, HGB haemoglobin, HCT haematocrit, PLT platelets, LYMP lymphocytes, MON monocytes, ENP EOSINOPHILS, NTP neutrophils