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Table 2 Haematological parameters of rats following 28-day repeated administration of Culcasia angolensis leaves extract (CAE)

From: Preliminary sub-acute toxicological assessment of methanol leaves extract of Culcasia angolensis (Araceae) in Wistar rats

Parameters

Treatment (mg/kg)

DW (1 ml/kg)

CAE (125)

CAE (250)

CAE (500)

WBC (× 109/L)

3.85 ± 0.27

4.07 ± 0.22

4.27 ± 0.10

3.85 ± 0.15

HGB (g/dL)

12.72 ± 0.33

12.62 ± 0.97

11.15 ± 0.69

11.12 ± 0.51

RBC (× 106/µL)

5.85 ± 0.17

5.98 ± 0.15

5.70 ± 0.14

5.93 ± 0.19

PLT (× 103/µL)

7.20 ± 0.10

7.18 ± 0.10

7.18 ± 0.11

7.08 ± 0.06

HCT (%)

37.16 ± 1.86

36.67 ± 3.18

35.00 ± 1.97

35.17 ± 1.30

MON (%)

2.33 ± 0.56

1.67 ± 0.21

1.50 ± 0.34

2.00 ± 0.37

LYMPH (%)

78.17 ± 1.17

77.67 ± 0.72

78.50 ± 0.99

81.33 ± 1.38*

ENP (%)

2.17 ± 0.30

1.66 ± 0.33

2.00 ± 0.36

1.83 ± 0.31

NTP (%)

17.33 ± 2.08

19.00 ± 0.97

18.00 ± 1.15

15.00 ± 0.97

  1. The values were tabulated as mean ± SEM, *p ≤ 0.05 in relation to the control group (one-way ANOVA followed by Dunnett’s post hoc test), n = 6
  2. DW distilled water, CAE Culcasia angolensis leaves extract, WBC white blood cell, RBC red blood cells, HGB haemoglobin, HCT haematocrit, PLT platelets, LYMP lymphocytes, MON monocytes, ENP EOSINOPHILS, NTP neutrophils