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Fig. 7 | Bulletin of the National Research Centre

Fig. 7

From: Simultaneous administration of coffee and rasagiline/l-dopa protects against paraquat-induced neurochemical and motor behavior impairments in vivo

Fig. 7

A Brain tissue of mice treated with (l-dopa + CAF + PQ) showing restored cellularity with several neuronal cells, non-pigmented with large rounded nuclei and prominent nucleoli (black arrow). Adjacent pyramidal pigmented neuronal cells were seen as well (white arrow). B Brain tissue of mice treated with (l-dopa + CAF + PQ) showing organized, cellular Purkinje cell layer with adjacent tissues showing marked improvement with no vacuolar degeneration (black arrows). C Brain tissue of mice treated with (l-dopa + CAF + PQ) showing prominent restored cellularity (black arrow). D Brain tissue of mice treated with (l-dopa + CAF + PQ) showing cellular tissue, with several oligodendroglial (black arrow) and pigmented neuronal cells (white arrow) together with markedly improved background with minimal residual vacuolar degeneration (H&E X400)

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