Modulatory effect of Persea Americana oil against diethylnitrosamine-induced hepatotoxicity in rats: a proposed mechanism

Bulletin of the National Research Centre

Table 2 Effect of PA oil and/or DEN on liver function test in normal rats

	ALT (U/L)	AST (U/L)	ALP (U/L)	Total protein (gm/dl)	Total bilirubin (mg/dl)	Direct bilirubin (mg/dl)
Group 1 (normal control)	12.3 ± 1.97	16.3 ± 1.86	122.5 ± 4.09	5.69 ± 0.38	0.87 ± 0.03	0.24 ± 0.02
Group 2 (DEN)	59.2 ± 5.49^ac	55.7 ± 13.4^ac	280.7 ± 36.52^ac	3. 61 ± 0.35^ac	2.25 ± 0.45^ac	0.79 ± 0.05^ac
Group 3 (PA oil)	15.7 ± 1.86^b	10.2 ± 1.47^b	123.8 ± 4.7^b	5.68 ± 0.36^b	0.87 ± 0.04^b	0.21 ± 0.03^b
Group 4 (DEN + PA oil)	33.5 ± 3.45^abc	24.8 ± 2.3^bc	184.7 ± 4.76^abc	4.3 ± 0.31^abc	1.37 ± 0.27^abc	0.55 ± 0.03^abc

The data is presented as Mean ± S.D. (n = 6). In the same column, “Mean values” with dissimilar superscript letters are significantly different at (P ≤ 0.05)
^aSignificant to normal control group (P ≤ 0.05)
^bSignificant to DEN group (P ≤ 0.05)
^cSignificant to PA oil group (P ≤ 0.05)