Efficacy of some Egyptian native plant extracts against Haemonchus contortus in vitro and in experimentally infected sheep along with the associated haematological and biochemical alterations

Hassan, Noha M. F.; Zaghawa, Ahmed A.; Abu-Elezz, Nadia M. T.; Nayel, Mohamed A.; Salama, Akram A.

doi:10.1186/s42269-021-00636-5

Bulletin of the National Research Centre

Table 5 Effect of various treatments on biochemical parameters of different experimental lamb groups

From: Efficacy of some Egyptian native plant extracts against Haemonchus contortus in vitro and in experimentally infected sheep along with the associated haematological and biochemical alterations

Parameter	Week	Experimental animals
Parameter	Week	G1	G2	G3	G4	G5
Serum total protein	0	7.03 ± .23 ^Aab	6.53 ± 0.26^Bb	6.97 ± 0.23 ^Aab	7.5 ± 0.14 ^Aa	6.53 ± 0.26 ^ABb
	3	5.87 ± .067 ^Ba	6.43 ± 0.23^Ba	4.9 ± 0.14 ^Cb	4.47 ± 0.37 ^Cb	5 ± 0.36^Db
	6	7.03 ± .23 ^Aab	6.53 ± 0.26^Bb	6.97 ± 0.23 ^Aab	7.5 ± 0.14 ^Aa	6.53 ± 0.26 ^ABb
	9	4.9 ± .057^Dc	7.53 ± .14^Aa	6.9 ± 0.20 ^Ab	7 ± 0.10 ^Aab	6.87 ± 0.29 ^ABb
Serum albumin	0	3.8 ± 0.23^Aa	3.5 ± 0.26^Ba	3.7 ± 0.26^ABa	3.9 ± 0.088^ABa	4.1 ± 0.32^Aa
	3	2.57 ± 0.17^Bb	4.47 ± 0.35^ABa	1.9 ± 0.08^Cbc	2.0 ± 0.13^Cbc	1.9 ± 0.10^Cc
	6	1.73 ± 0.12^Db	4.1 ± 0.17^ABa	3.97 ± 0.088^Aa	4.07 ± 0.14^ABa	4.17 ± 0.088 ^Aa
	9	1.8 ± 0.033^Db	4.77 ± 0.26^Aa	4.37 ± 0.21 ^Aa	4.47 ± 0.37^Aa	4.2 ± 0.20 ^Aa
A/G ratio	0	1.2 ± 0.20 ^Aa	1.2 ± 0.31^Aa	1.2 ± 0.18 ^Aa	1.09 ± 0.00 ^ABa	1.8 ± 0.44 ^Aa
	3	0.79 ± 0.11^Bb	2.6 ± 0.68 ^Aa	0.64 ± 0.05 ^Ab	0.90 ± 0.20^Bb	0.63 ± 0.09^Bb
	6	0.53 ± 0.04 ^Bb	1.5 ± 0.23 ^Aa	1.4 ± 0.12 ^Aa	1.5 ± 0.22 ^ABa	1.8 ± 0.19 ^Aa
	9	0.59 ± 0.02 ^Bb	1.8 ± 0.36 ^Aa	1.8 ± 0.32 ^Aa	1.8 ± 0.43^Aa	1.6 ± 0.31 ^Aa
SGOT	0	11.07 ± 0.38^Da	12.73 ± 2.14^Aa	12.57 ± 1.18^Ba	12.53 ± 1.92 ^Ba	11.50 ± 0.52^Ba
	3	13.00 ± 0.23^Cab	11.97 ± 1.27 ^Ab	15.93 ± 1.56^Aa	15.73 ± 1.4 ^Aab	13.73 ± 0.66 ^Aab
	6	16.60 ± 0.35 ^Aa	11.73 ± 0.26 ^Abc	11.43 ± 0.23 ^Bbc	10.87 ± 0.35 ^Bc	12.50 ± 0.50^ABb
	9	13.60 ± 0.32 ^BCa	11.63 ± 0.69 ^Ab	11.57 ± 0.40 ^Bb	10.70 ± 0.20 ^Bb	11.83 ± 0.12 ^Bb
SGPT	0	24.6 ± 4.4^Ba	31.4 ± 11.9^Aa	25 ± 1.8^Ca	28.97 ± 4.7 ^Ba	33.4 ± 2.5^Ba
	3	42.8 ± 7.7 ^Aab	30.1 ± 9.8 ^Ab	47.7 ± 6.17^Aab	54.23 ± 4.0^Aa	56.2 ± 4.1^Aa
	6	43.3 ± 3.6 ^Aa	32.4 ± 9.4 ^Aa	32 ± 3.30 ^BCa	28.7 ± 5.8 ^Ba	34.4 ± 1.2 ^Ba
	9	40.7 ± 0.93 ^ABa	29.6 ± 9.2 ^Aa	27.4 ± 1.43^Ca	28.27 ± 4.9 ^Ba	33.6 ± 5.0 ^Ba
BUN	0	15.47 ± 2.0^Ca	13.1 ± 1.10^Aa	14.1 ± 1.9^Aa	13.57 ± 1.2^Ba	15.3 ± 1.4^BCa
	3	18.1 ± 2.26 ^BCa	11.2 ± 0.23^Bb	17.6 ± 2.0 ^Aa	17.3 ± 0.75^Aa	19.9 ± 1.2^Aa
	6	21.5 ± 0.36 ^ABa	10.8 ± 0.47^Bc	15.0 ± 0.86 ^Ab	10.7 ± 0.12^Dc	15.6 ± 0.26 ^BCb
	9	23.47 ± 0.87 ^Aa	11.0 ± 0.31^Bc	14.37 ± 1.09 ^Ab	10.9 ± 0.26 ^CDc	13.7 ± 0.79^Cb
Serum creatinine	0	0.95 ± 0.08^Ca	1.0 ± 0.16^ABa	1.07 ± 0.08 ^Ba	1.1 ± 0.10 ^Ca	1.2 ± 0.03 ^BCa
	3	1.8 ± 0.05^Ba	0.93 ± 0.06^Bc	1.6 ± 0.05^Aab	1.5 ± 0.06 ^Ab	1.5 ± 0.07 ^Ab
	6	2.1 ± 0.35^ABa	1.27 ± 0.06^Ab	1.1 ± 0.05 ^Bb	1.1 ± 0.12^BCb	1.0 ± 0.06^Db
	9	1.8 ± 0.05^Ba	1.06 ± 0.12 ^ABb	1.0 ± 0.04 ^Bb	1.0 ± 0.09 ^Cb	1.0 ± 0.06 ^Db

G, lambs group
Capital letters: means within the same column of different letters are significantly different at (P < 0.01). Small letters: means within the same row of different letters are significantly different at (P < 0.01)

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