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Table 8 Predicted Drug-likeness properties of the designed compounds

From: Chemo-informatics activity prediction, ligand based drug design, Molecular docking and pharmacokinetics studies of some series of 4, 6-diaryl-2-pyrimidinamine derivatives as anti-cancer agents

S/NO

MW

HBD

HBA

WlogP

Lipinski violation

Bio availability score

Drug likeness

N1

582.69

3

7

4.65

1

0.55

YES

N2

581.70

3

7

5.71

1

0.55

YES

N3

582.69

3

7

4.65

1

0.55

YES

N4

569.65

3

8

4.59

1

0.55

YES

N5

634.52

3

8

5.05

1

0.55

YES