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Table 4 Adverse health effects associated with toxic levels of selected heavy metals

From: A review of the health implications of heavy metals and pesticide residues on khat users

Health effects

Physiological symptoms associated with the heavy metal

Heavy metals determined in khat

References

Cardiovascular diseases

Heart rate increase, Dry mouth, Blurred vision

Pb, Cd, Cu

Chowdhury et al. (2018)

Gastrointestinal disorders

Diarrhea, Nausea, Vomiting, Abdominal pain

Cu, Mn, Fe, Co, Cd

Pizzaro et. al. (1999), Sane et al. (2018), Leyssens et. al. (2017), Lia et al. (2019), Tinkov et al. (2018)

Reproductive disorders

Hampered fetal growth, Fertility disorders

Pb

Kumar et al. (2020)

Carcinogenic effects

Tumor growth

Cd

Genchi et al. (2020)

Neurological disorders

Reduced intelligence quotient (IQ) in children, Mental retardation, Behavioral disorders, Suicide attempts

Pb, Cu, Mn, Fe

WHO (2019), Santos et. al. (2019), Dobson et al. (2004), Sane et al. (2018)