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Table 1 A list of different SARS-CoV-2 variants that occurred globally

From: SARS-CoV-2 infection: a global outbreak and its implication on public health

COVID variant Substitutions in spike protein Origin Characteristics References
B.1.1.7 Δ69/70, Δ144, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H UK Approx. 50% transmission
No impact with monoclonal antibody treatment
Wang et al. (2021)
B.1.351 D80A, D215G, Δ241/242/243, K417N, E484K, N501Y, D614G, A701V South Africa Approx. 50% transmission
Decrease with combination of bamlanivimab and etesevimab and monoclonal antibody treatment
Wu et al. (2021), Wang et al. (2021)
B.1.427 L452R, D614G USA Approx. 20% transmission
Less chance of decrease with combination of bamlanivimab and etesevimab and monoclonal antibody treatment
Zhou et al. (2021)
B.1.429 S13I, W152C, L452R, D614G USA Approx. 20% transmission
Less chance of decrease with combination of bamlanivimab and etesevimab and monoclonal antibody treatment
Zhou et al. (2021)
P.1 L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I Brazil and Japan Decrease with combination of bamlanivimab and etesevimab and monoclonal antibody treatment Zhou et al. (2021)
B.1.526 T95I, D253G, D614G USA Decrease with combination of bamlanivimab and etesevimab and monoclonal antibody treatment Annavajhala et al. (2021)
B.1.526.1 Spike: D80G, Δ144, F157S, L452R, D614G, (T791I*), (T859N*), D950H USA Reduction in neutralization by some EUA monoclonal antibody treatments Annavajhala et al. (2021)
B.1.525 Spike: A67V, Δ69/70, Δ144, E484K, D614G, Q677H, F888L UK/Nigeria EUA monoclonal antibody treatments Zhou et al. (2021)
P.2 Spike: E484K, (F565L*), D614G, V1176F Brazil EUA monoclonal antibody treatments Zhou et al. (2021)
B.1.617 Spike: L452R, E484Q, D614G India Potential reduction in neutralization by some EUA monoclonal antibody treatments Yadav et al. (2021)
B.1.617.1 Spike: (T95I), G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H India EUA monoclonal antibody treatments Yadav et al. (2021)
B.1.617.2 Spike: T19R, (G142D), Δ156, Δ157, R158G, L452R, T478K, D614G, P681R, D950N India EUA monoclonal antibody treatments Yadav et al. (2021)
B.1.617.3 Spike: T19R, G142D, L452R, E484Q, D614G, P681R, D950N India EUA monoclonal antibody treatments Yadav et al. (2021)