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Bulletin of the National Research Centre

Table 1 Action of methanol bark extract of Hymenocardia acida on castor oil-induced diarrhoea in mice

From: Antidiarrhoeal potentials of methanol bark extract of Hymenocardia Acida Tul (Euphorbiaceae) in laboratory animals

Treatments (mg/kg, p.o)

Onset of diarrhoea (min)

Number of dry faeces

Number of wet faeces

Percentage inhibition (%)

DW 10 ml/kg

27.20 ± 4.71

2.60 ± 0.98

5.20 ± 0.49

 

MEHA (150)

76.80 ± 7.35*

2.00 ± 0.32

4.00 ± 0.71

23.08

MEHA (300)

82.80 ± 3.06*

1.20 ± 0.80

2.40 ± 0.68*

53.85

MEHA (600)

83.20 ± 6.36*

1.00 ± 0.45

1.00 ± 0.45*

80.77

LOP (3)

93.80 ± 2.31*

1.00 ± 0.32

0.20 ± 0.20*

96.15

  1. The values are represented as mean ± SEM; *p < 0.05, compared to the distilled water group (one-way ANOVA followed by Dunnett's post hoc test), DW = distilled water, MEHA = methanol stem bark extract of H. acida, LOP = loperamide, p.o = per oral, n = 6
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