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Table 1 Action of methanol bark extract of Hymenocardia acida on castor oil-induced diarrhoea in mice

From: Antidiarrhoeal potentials of methanol bark extract of Hymenocardia Acida Tul (Euphorbiaceae) in laboratory animals

Treatments (mg/kg, p.o) Onset of diarrhoea (min) Number of dry faeces Number of wet faeces Percentage inhibition (%)
DW 10 ml/kg 27.20 ± 4.71 2.60 ± 0.98 5.20 ± 0.49  
MEHA (150) 76.80 ± 7.35* 2.00 ± 0.32 4.00 ± 0.71 23.08
MEHA (300) 82.80 ± 3.06* 1.20 ± 0.80 2.40 ± 0.68* 53.85
MEHA (600) 83.20 ± 6.36* 1.00 ± 0.45 1.00 ± 0.45* 80.77
LOP (3) 93.80 ± 2.31* 1.00 ± 0.32 0.20 ± 0.20* 96.15
  1. The values are represented as mean ± SEM; *p < 0.05, compared to the distilled water group (one-way ANOVA followed by Dunnett's post hoc test), DW = distilled water, MEHA = methanol stem bark extract of H. acida, LOP = loperamide, p.o = per oral, n = 6