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Bulletin of the National Research Centre
Fig. 6 | Bulletin of the National Research Centre

Fig. 6

From: Metformin induces apoptosis via uterus mitochondrial permeability transition pore opening and protects against estradiol benzoate-induced uterine defect and associated pathophysiological disorder in female Wistar rats

Fig. 6

Photomicrographs showing the effect of metformin on the myometrium of normal and EB-treated female rats using collagen Masson’s trichome stain (a) (Mag. X 400). Cell count density obtained from the myometrium of uterus of control and the EB-treated groups (b). Control and MTF: Plates show moderate deposition of collagen fiber. EB: Plates show high deposition of collagen fibers within the myometrium coupled with severe hyperplasia. EB + MTF: Plates show reduction of collagen fiber within the myometrium and attenuation of the EB-induced uterine hyperplasia

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