Fig. 6From: Metformin induces apoptosis via uterus mitochondrial permeability transition pore opening and protects against estradiol benzoate-induced uterine defect and associated pathophysiological disorder in female Wistar ratsPhotomicrographs showing the effect of metformin on the myometrium of normal and EB-treated female rats using collagen Masson’s trichome stain (a) (Mag. X 400). Cell count density obtained from the myometrium of uterus of control and the EB-treated groups (b). Control and MTF: Plates show moderate deposition of collagen fiber. EB: Plates show high deposition of collagen fibers within the myometrium coupled with severe hyperplasia. EB + MTF: Plates show reduction of collagen fiber within the myometrium and attenuation of the EB-induced uterine hyperplasiaBack to article page