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Table 11 Statistical analysis of the descriptor used in the QSAR model

From: QSAR, molecular docking studies, ligand-based design and pharmacokinetic analysis on Maternal Embryonic Leucine Zipper Kinase (MELK) inhibitors as potential anti-triple-negative breast cancer (MDA-MB-231 cell line) drug compounds

 

AATS6i

ATSC8i

GATS5s

VR1_Dze

C2SP3

VIF

P value

AATS6i

1

    

2.077006

0.006999

ATSC8i

0.374295

1

   

1.272532

0.000162

GATS5s

−0.65093

−0.3855

1

  

1.984035

3.01E−05

VR1_Dze

0.000492

−0.16932

0.0273

1

 

1.059332

0.000661

C2SP3

0.280075

0.185489

0.013492

−0.15324

1

1.226411

−4.6729