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Table 3 Significant genes with their expression on SARS-CoV-2

From: Identification of selected genes associated with the SARS-CoV-2: a therapeutic approach and disease severity

S. no. Major genes Complications
1 ACE-2 (angiotensin-converting enzyme 2) IT affects CNS and infects certain brain areas entering the olfactory bulb and thereby leading to loss of olfaction (Yin et al. 2020; Rodríguez-Puertas 2020)
2 IL-2, IL-7, and IL-10 (interleukins) Autoimmune and immunostimulatory effects (Rodríguez-Puertas 2020). Negative regulation of transforming growth factor-β (Rousset et al. 2020)
3 TNF (tumor necrosis factor) Depletion of T lymphocytes (Pellegrini et al. 2011)
4 VEGF (vascular endothelial growth factor) Exacerbating edema and the outbreak of immune cells (Diao et al. 2019b)