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Table 2 Serum BMP-2 (ng/L) activity among the studied groups

From: The role of VEGF and BMP-2 in stimulation of bone healing with using hybrid bio-composite scaffolds coated implants in animal model

Parameters Groups
Group I Group II Group III Group IV
Control CH (NM) CH (M) CH.BG (NM) CH.BG (M)
Range 0.035-1.879 1.051-2.892 0.779-2.881 0.654-1.197
Pre-surgery     
Mean ± S.D 1.77 ± 0.24 3.206 ± 0.018 2.358 ± 0.008 3.555 ± 0.01
(2-week)     
Mean ± S.D 5.459 ± 0.019 8.355 ± 0.0098 8.411 ± 0.011 2.441 ± 0.015
P value   < 0.001* < 0.001** < 0.001***
(3-week)     
Mean ± S.D 5.209 ± 0.011 4.936 ± 0.91 6.976 ± 0.087 2.449 ± 0.069
P value   NS < 0.001** < 0.001***
(4-week)8     
Mean ± S.D 4.906 ± 0.009 6.821 ± 0.699 2.953 ± 0.01 2.697 ± 0.029
P value   < 0.05* < 0.001** < 0.001***
(5-week)     
Mean ± S.D 4.781 ± 0.007 4.421 ± 0.042 7.929 ± 0.06 2.628 ± 0.07
P value   < 0.001* < 0.001** = 0.001***
(6-week)     
Mean ± S.D 4.921 ± 0.021 5.094 ± 0.333 7.716 ± 0.058 2.625 ± 0.166
P value   < 0.001* < 0.001** < 0.05***
(7-week)     
Mean ± S.D 5.424 ± 0.017 7.853 ± 0.468 7.825 ± 0.01 3.008 ± 0.094
P value   < 0.05 * < 0.001** < 0.05***
(8-week)     
Mean ± S.D 5.322 ± 0.117 8.109 ± 0.0085 6.841 ± 0.0081 2.761 ± 0.059
P value   < 0.001* < 0.001** = 0.001***
(9-week)     
Mean ± S.D 4.834 ± 0.016 7.467 ± 0.065 6.551 ± 0.098 2.314 ± 0.175
P value   < 0.001* < 0.001** < 0.05***
(10-week)     
Mean ± S.D 5.04 ± 0.019 6.011 ± 0.367 6.162 ± 0.009 2.568 ± 0.175
P value   < 0.05* < 0.001** < 0.05***
(11-week)     
Mean ± S.D 5.36 ± 0.068 5.338 ± 0.104 8.64 ± 0.0009 2.294 ± 0.008
P value   < 0.05* < 0.001** < 0.001***
(12-week)     
Mean ± S.D 5.338 ± 0.104 2.33 ± 0.087 7.575 ± 0.09 2.33 ± 0.087
P value   < 0.05* < 0.001** = 0.001***
  1. P > 0.05 is non-significant, P ≤ 0.05 is significant, P ≤ 0.001 is highly significant, NS non-significant
  2. *P value between group I versus group II
  3. **P value between group I versus group III
  4. ***P value between group I versus group IV