TY - JOUR AU - Egbubine, Chiedozie O. AU - Adeyemi, Modupe M. AU - Habila, James D. PY - 2020 DA - 2020/04/06 TI - Isolation and characterization of betulinic acid from the stem bark of Feretia canthioides Hiern and its antimalarial potential JO - Bulletin of the National Research Centre SP - 49 VL - 44 IS - 1 AB - Malaria is a parasitic disease that constitutes a major global health concern and the increasing resistance of Plasmodium falciparum strains to the commonly used antimalarial drugs has resulted in an increase in treatment failures (Zofou et al.,Malar Res Treat: 561342, 2011). Natural products isolated from plants used in traditional medicine have shown promising antimalarial actions in vitro, and these plants can serve as potential sources for new antimalarial drugs (Wright et al.,Phytother Res 8:149–152, 1994); hence, research into the use of medicinal plants for the treatment of malaria would provide viable options in the effective control of the disease by screening plant extracts for antimalarial activities and also isolating bioactive components from these extracts using TLC and column chromatographic techniques. SN - 2522-8307 UR - https://doi.org/10.1186/s42269-020-00302-2 DO - 10.1186/s42269-020-00302-2 ID - Egbubine2020 ER -