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Table 1 Description of studies identified as relevant in the systematic literature search looking for an association between T. gondii and diabetes mellitus

From: The association between Toxoplasma gondii and type 2 diabetes mellitus: a systematic review and meta-analysis of human case-control studies

ReferenceYear publishedCountryDiabetesStudy typeSource 1DefinitionSource 2Matching*Measure of exposure
Li et al. (Li et al. 2018)2018ChinaT1 + 2DMCCHospitalUnspecifiedHospitalYesIgG/IgM ELISA (Demeditec Diagnostics, Germany)
Khalili et al. (Khalili et al. 2018)2018IranT1 + 2DMCCClinicsUnspecifiedClinicsYesIgG/IgM CLIA (Disorin, Italy)
Han et al. (Han et al. 2018)2018ChinaT2DMCaseHospitalYesN/AN/AIgG ELISA (Haitai Biological Pharmaceuticals, China)
Molan & Ismail (Molan and Ismail 2017)2017IraqT1 + 2DMCCClinicsUnspecifiedClinicsNoIgG/IgM ELISA (ACON Labs, USA)
Alvarado-Esquivel et al. (Alvarado-Esquivela et al. 2017)2017BrazilT1 + 2DMCCClinicsUnspecifiedClinicsYesIgG ELIFA & VIDAS ELFA IgM (BioMerieux, France)
Saheb (Saheb 2017)2017IraqT2DMCCClinicsUnspecifiedClinicsNoIgG ELISA (BioCheck Inc., USA)
Nihad & Hamad (Nihad and Hamad 2017)2017IraqDiabeticCCHospitalUnspecifiedHospitalNoIgG/IgM ELISA (BioCheck Inc., USA)
Hemida et al. (Hemida et al. 2017)2017EgyptT1 + 2DMCaseHospitalUnspecifiedN/AN/AIgG/IgM ELISA (Calbiotech Inc., USA)
Saki et al. (Saki and Shafieenia 2016)2016IranDiabeticCCHospitalUnspecifiedHospitalNoIgG/IgM ELISA (Trinity Biotech, USA) & IFAT kit
Modrek et al. (Modrek et al. 2015a)2015IranDiabeticCaseHospitalUnspecifiedN/AN/AIgG/IgM (DRG instrument GmbH, Germany)
Siyadatpanah et al. (Siyadatpanah et al. 2013)2013IranDiabeticCCHospitalUnspecifiedHospitalYesIgG/IgM ELISA (VIRO, Germany)
Shirbazou et al. (Shirbazou et al. 2013)2013IranDiabeticCCUnspecifiedUnspecifiedUnspecifiedYesIgG ELISA (Pishtaz Teb Zaman Diagnostics, Iran)
Gokce et al. (Gokce et al. 2008)2008TurkeyT2DMCCUnspecifiedADAUnspecifiedYesIgG/IgM ELISA and IFAT (Euroimmun)
  1. *Matching is by age and gender alone; source 1, source of diabetes mellitus cases; source 2, source of non-type 2 diabetes mellitus controls; definition, definition of diabetes mellitus cases. Highlight signifies the studies retained for the meta-analysis (Table 2)
  2. CC case-control, IgG immunoglobulin G, IgM immunoglobulin M, ELISA enzyme-linked immunosorbent assay, CLIA chemiluminescence immunoassay, ELIFA enzyme-linked immunofiltration assay, ELFA enzyme-linked fluorescent assay, IFAT immunofluorescence antibody test