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Table 1 Description of studies identified as relevant in the systematic literature search looking for an association between T. gondii and diabetes mellitus

From: The association between Toxoplasma gondii and type 2 diabetes mellitus: a systematic review and meta-analysis of human case-control studies

Reference Year published Country Diabetes Study type Source 1 Definition Source 2 Matching* Measure of exposure
Li et al. (Li et al. 2018) 2018 China T1 + 2DM CC Hospital Unspecified Hospital Yes IgG/IgM ELISA (Demeditec Diagnostics, Germany)
Khalili et al. (Khalili et al. 2018) 2018 Iran T1 + 2DM CC Clinics Unspecified Clinics Yes IgG/IgM CLIA (Disorin, Italy)
Han et al. (Han et al. 2018) 2018 China T2DM Case Hospital Yes N/A N/A IgG ELISA (Haitai Biological Pharmaceuticals, China)
Molan & Ismail (Molan and Ismail 2017) 2017 Iraq T1 + 2DM CC Clinics Unspecified Clinics No IgG/IgM ELISA (ACON Labs, USA)
Alvarado-Esquivel et al. (Alvarado-Esquivela et al. 2017) 2017 Brazil T1 + 2DM CC Clinics Unspecified Clinics Yes IgG ELIFA & VIDAS ELFA IgM (BioMerieux, France)
Saheb (Saheb 2017) 2017 Iraq T2DM CC Clinics Unspecified Clinics No IgG ELISA (BioCheck Inc., USA)
Nihad & Hamad (Nihad and Hamad 2017) 2017 Iraq Diabetic CC Hospital Unspecified Hospital No IgG/IgM ELISA (BioCheck Inc., USA)
Hemida et al. (Hemida et al. 2017) 2017 Egypt T1 + 2DM Case Hospital Unspecified N/A N/A IgG/IgM ELISA (Calbiotech Inc., USA)
Saki et al. (Saki and Shafieenia 2016) 2016 Iran Diabetic CC Hospital Unspecified Hospital No IgG/IgM ELISA (Trinity Biotech, USA) & IFAT kit
Modrek et al. (Modrek et al. 2015a) 2015 Iran Diabetic Case Hospital Unspecified N/A N/A IgG/IgM (DRG instrument GmbH, Germany)
Siyadatpanah et al. (Siyadatpanah et al. 2013) 2013 Iran Diabetic CC Hospital Unspecified Hospital Yes IgG/IgM ELISA (VIRO, Germany)
Shirbazou et al. (Shirbazou et al. 2013) 2013 Iran Diabetic CC Unspecified Unspecified Unspecified Yes IgG ELISA (Pishtaz Teb Zaman Diagnostics, Iran)
Gokce et al. (Gokce et al. 2008) 2008 Turkey T2DM CC Unspecified ADA Unspecified Yes IgG/IgM ELISA and IFAT (Euroimmun)
  1. *Matching is by age and gender alone; source 1, source of diabetes mellitus cases; source 2, source of non-type 2 diabetes mellitus controls; definition, definition of diabetes mellitus cases. Highlight signifies the studies retained for the meta-analysis (Table 2)
  2. CC case-control, IgG immunoglobulin G, IgM immunoglobulin M, ELISA enzyme-linked immunosorbent assay, CLIA chemiluminescence immunoassay, ELIFA enzyme-linked immunofiltration assay, ELFA enzyme-linked fluorescent assay, IFAT immunofluorescence antibody test