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Table 1 Time-dependent effect of etoposide on radicle length and mitotic cell division

From: Effect of etoposide on grass pea DNA topoisomerase II: an in silico, in vivo, and in vitro assessments

Treatment of drug (etoposide) for time dependent manner

Etoposide concentration (μM)

24 h

48 h

72 h

Radicle length (mm)

Mitotic index %

Radicle length (mm)

Mitotic index %

Radicle length (mm)

Mitotic index %

Control

19.70 ± 1.2

9.02

19.70 ± 1.2

9.02

19.7 ± 1.2

9.02

50

16.21 ± 1.3

5.40

12.44 ± 1.6

4.90

10.4 ± 0.9

3.66

100

12.84 ± 1.2

5.00

10.60 ± 0.8

3.00

8.3 ± 0.7

1.01

150

10.36 ± 0.9

3.40

6.32 ± 0.9

1.30

3.9 ± 0.7

0.05

LSD (P ≤ 0.05)

1.22

0.67

0.52

0.39

0.75

0.35