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Bulletin of the National Research Centre
Fig. 1 | Bulletin of the National Research Centre

Fig. 1

From: Effect of etoposide on grass pea DNA topoisomerase II: an in silico, in vivo, and in vitro assessments

Fig. 1

The etoposide-binding region inside the cleavage core of topoisomerase II is shown with WebLogo result. Conserve amino acid sequences of 38 different plant species and human are represented in this cleavage core. The data for this logo consists of 40 amino acids. The chemical structure of the drug and its interacting sites (G-478, D-479, L-502, R-503) (above) and topoII domain structure (below) are shown in the figure

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