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Table 3 Correlation analysis of serum biomarkers with confounding parameters in RVVI, RVVI types, and controls

From: Impaired PRR expression modulates inflammation-triggered oxidative stress and pathogenesis of recurrent vulvovaginal infections

  sMBL sDectin-1 sTAC sTOS sOSI
r p r p r p r p r p
RVVI
 Age − 0.006 0.460 − 0.076 0.112 − 0.104 0.048* − 0.073 0.122 0.052 0.204
 RCBG 0.016 0.401 − 0.062 0.169 − 0.125 0.023* − 0.021 0.368 0.006 0.465
 Age of initiation of sexual activity 0.129 0.019* − 0.153 0.163 − 0.233 0.000*** − 0.097 0.060 0.023 0.354
 Duration of infection 0.073 0.121 − 0.064 0.139 − 0.019 0.379 − 0.016 0.399 0.016 0.401
BV
 Age − 0.002 0.491 − 0.095 0.178 − 0.153 0.067 − 0.164 0.054 0.058 0.286
 RCBG 0.050 0.314 0.196 0.027* − 0.124 0.113 − 0.108 0.146 − 0.079 0.222
 Age of initiation of sexual activity 0.280 0.003** − 0.187 0.034* − 0.321 0.001*** − 0.097 0.173 0.129 0.104
 Duration of infection − 0.047 0.323 − 0.095 0.178 − 0.107 0.149 − 0.074 0.237 0.169 0.049*
VVC
 Age 0.043 0.369 − 0.348 0.003** − 0.083 0.261 0.217 0.045* 0.205 0.055
 RCBG − 0.005 0.486 − 0.227 0.038* − 0.146 0.128 0.212 0.049* 0.123 0.170
 Age of initiation of sexual activity 0.132 0.154 − 0.285 0.012* − 0.303 0.008** 0.151 0.121 0.183 0.077
 Duration of infection 0.357 0.002** − 0.105 0.208 0.157 0.112 − 0.010 0.471 − 0.171 0.092
MI
 Age 0.005 0.459 0.026 0.436 − 0.132 0.206 − 0.247 0.060 0.040 0.401
 RCBG − 0.022 0.445 − 0.051 0.375 − 0.208 0.096 − 0.159 0.160 0.008 0.480
 Age of initiation of sexual activity 0.459 0.001*** 0.103 0.261 − 0.034 0.417 − 0.354 0.012* − 0.318 0.021*
 Duration of infection − 0.267 0.046* − 0.207 0.097 − 0.046 0.388 − 0.335 0.016* 0.024 0.441
HC
 Age − 0.090 0.101 0.045 0.263 0.044 0.265 − 0.032 0.323 − 0.093 0.094
 RCBG − 0.054 0.221 − 0.071 0.157 − 0.022 0.378 0.158 0.012* 0.051 0.236
 Age of initiation of sexual activity 0.014 0.421 0.026 0.354 0.036 0.307 0.027 0.353 − 0.005 0.473
  1. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001