In vitro assessment of hypocholesterolemic activity of Lactococcus lactis subsp. lactis

Bulletin of the National Research Centre

Table 4 Deconjugation of glycocholate and taurocholate or their combination by Lactococcus lactic subsp. lactis^{a, b}

Conjugated bile salt	Cholic acid released (mM)^{a, b}
Sodium glycocholate (6 mM)	1.39 ± 0.43^c
Sodium taurocholate (6 mM)	0.74 ± 0.25^c
Sodium glycocholate (2.8 mM) + sodium taurocholate (1.2 mM)	1.46 ± 0.49^c

Deconjugation of glycine- or taurine-conjugated bile salt based on the released cholic acid
^aMRS broth supplemented with either sodium glycocholate (6 mM), sodium taurocholate (6 mM), or a mixture of sodium glycocholate (2.8 mM) and sodium taurocholate (1.2 mM)
^bMeans in the same column followed by different lowercase letters are significantly different (p < 0.05)
^cResults are expressed as the means ± standard error of the means, values are the means of triplicate measurements