Potential prophylactic effect of chemical chaperones for alleviation of endoplasmic reticulum stress in experimental diabetic cataract

Table 3 Blood glutathione (GSH), serum malondialdehyde (MDA), and serum total antioxidant capacity (TAC) in control and experimental groups

Groups	GSH mg/dl erythrocyte	MDA nmol/ml	TAC mmol/L
Group 1: control
Range	75–101.5	2.2–4.1	2.1–3.2
Mean ± S.D	85.9 ± 7.52	3.027 ± 0.52	2.74 ± 0.35
Group 2: diabetic model
Range	20–41	8.6–12.8	0.9–1.9
Mean ± S.D	26.53 ± 6.35^a	10.35 ± 1.39^a	1.39 ± 0.27^a
Group 3: diabetic model + 4PBA
Range	72–94	3.8–8.6	2–2.6
Mean ± S.D	84.4 ± 6^b	6.18 ± 1.53^a,b	2.28 ± 0.22^a,b
Group 4: diabetic model + TUDCA
Range	55–95	4.8–8.4	1.9–2.9
Mean ± S.D	72.8 ± 11.9^a,b	6.34 ± 1.11^a,b	2.119 ± 0.24^a,b
Group 5: diabetic model + TMAO
Range	46–88	2.8–5.7	2–2.5
Mean ± S.D	58.26 ± 10.56^a,b	4.213 ± 0.89^a,b	2.229 ± 0.14^a,b