Table 3 Effect of daily caffeine treatment (30 mg/kg) on the levels of lipid peroxidation (MDA) (nmol/g), reduced glutathione (GSH) (mmol/g), and nitric oxide (NO) (μmol/g) in the cortex and hippocampus of rat model of depression induced by reserpine

Cortex

MDA

7.326^a ± 0.786 (6)

10.373^b ± 1.147 (6)

7.687^a ± 0.792 (6)

GSH

6.445^a ± 0.138 (7)

6.080^a ± 0.280 (7)

7.093^b ± 0.226 (7)

NO

0.194^a ± 0.016 (6)

0.240^b ± 0.014 (6)

0.272^b ± 0.013 (7)

Hippocampus

MDA

5.046^a ± 0.798 (6)

9.827^b ± 1.895 (6)

4.516^a ± 1.033 (6)

GSH

15.406^a ± 0.328 (6)

13.031^b ± 0.531 (6)

15.879^a ± 0.625 (7)

NO

0.459^a ± 0.044 (6)

0.825^b ± 0.082 (6)

0.564a^b ± 0.039 (7)