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Table 7 Therapeutic effect of P. ovata seed carbohydrates and fixed oil on DNA fragmentation indices of liver tissue in ketoprofen toxicity rats

From: A therapeutic insight of carbohydrate and fixed oil from Plantago ovata L. seeds against ketoprofen-induced hepatorenal toxicity in rats

Groups % Tailed DNA % Untailed DNA DNA tail length (μm) % Total DNA Tail moment
Control 5.00 95.00 1.35f ± 0.13 1.21 1.63
P. ovata seed carbohydrates 4.00 96.00 1.33f ± 0.05 1.23 1.64
P. ovata seeds oil 5.00 95.00 1.29f ± 0.03 1.27 1.64
Ketoprofen 16.00 84.00 2.85a ± 0.04 2.79 7.95
Ketoprofen +
P. ovata seed carbohydrates
11.00 89.00 2.31d ± 0.08 2.24 5.17
Ketoprofen +
P. ovata seeds oil
13.00 87.00 2.59 b ± 0.02 2.51 6.50
Ketoprofen +
Silymarin.
9.00 91.00 2.11e ± 0.06 2.05 4.33
Ketoprofen left 1 week for recovery 14.00 86.00 2.48abc ± 0.04 2.44 6.05
Ketoprofen left 2 weeks for recovery 14.00 86.00 2.57ab ± 0.02 2.49 6.35
Ketoprofen left 3 weeks for recovery 12.00 88.00 2.42abcd ± 0.02 2.31 5.59
  1. Values are % of the total counts in each assay
  2. Tail Moment (unit) = tail length x % total DNA
  3. Data in DNA tail length are expressed as mean ± SD of three reading
  4. Groups having the same letters are non-significant while others having different letters are significant at p < 0.05