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Table 6 Therapeutic effect of P. ovata seed carbohydrates and fixed oil on liver function enzymes of ketoprofen toxicity in rats

From: A therapeutic insight of carbohydrate and fixed oil from Plantago ovata L. seeds against ketoprofen-induced hepatorenal toxicity in rats

Groups AST(Unit/L) ALT(Unit/L) ALP (Unit/L)
Control 53.73e ± 3.88
17.82e ± 3.38
125.93f ± 5.43
P. ovata seed carbohydrates 56.17e ± 2.66
(+ 4.54)
21.90e ± 1.28
(+ 22.89)
134.57f ± 6.86
(+ 6.86)
P. ovata seeds oil 62.02e ± 2.20
(+ 15.43)
22.30e ± 2.69
(+ 25.14)
140.81f ± 8.05
(+ 11.81)
Ketoprofen 147.40a ± 9.16
(+ 174.23)
63.32a ± 2.85
(+ 255.33)
221.56a ± 10.96
(+ 75.93)
Ketoprofen +
P. ovata seed carbohydrates
73.43d ± 7.67
[− 50.18]
37.41d ± 6.07
[− 40.91]
163.43e ± 6.23
[− 26.23]
Ketoprofen +
P. ovata seeds oil
82.81cd ± 8.15
[− 43.81]
46.50c ± 4.89
[− 26.56]
190.93cd ± 11.05
[− 13.82]
Ketoprofen +
Silymarin.
75.94d ± 4.44
[− 48.48]
31.77d ± 3.48
[− 49.82]
181.56d ± 17.71
[− 18.05]
Ketoprofen left 1 week for recovery 106.16b ± 10.19
[− 27.97]
61.47a ± 5.68
[− 2.92]
220.62a ± 7.73
[− 0.42]
Ketoprofen left 2 weeks for recovery 99.43b ± 7.67
[− 32.54]
60.35a ± 4.73
[− 4.70]
209.68ab ± 7.93
[−5.36]
Ketoprofen left 3 weeks for recovery 88.81c ± 9.08
[− 39.74]
53.11b ± 5.51
[− 16.12]
201.87bc ± 10.82
[− 8.88]
  1. Data are mean ± SD of six rats/group
  2. Groups having the same letters are non- significantly different, while those having different letters are significantly different at p < 0.05
  3. Values between brackets are % changes over control group
  4. Values between parentheses are % changes over ketoprofen group