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Table 1 Comparing the studied groups regarding liver function tests

From: Changes in tryptophan and phenylalanine in chronic HCV patients treated with direct acting antiviral (sofosbuvir)

Variable Untreated HCV cases (n = 40) Treated HCV cases (n = 40) Controls (n = 20) KW test p
Mean ± SD Range Mean ± SD Range Mean ± SD Range
Age (years) 45.8 11.0 22–65 51.5 12.2 32–77 46.1 12.6 20–67 ANOVA 2.66 0.075 (NS)
ALT (U/l) 24.7 7.54 13–37 28.3 11.56 13–51 18.9 6.02 10–33 9.42 0.009 (S)
AST (U/l) 28.9 8.28 19–44 36.6 11.03 20–60 25.8 6.69 16–38 17.8 < 0.001 (HS)
Albumin (g/dl) 3.95 0.66 2.1–5.1 3.90 0.64 2.2–4.9 4.13 0.50 3.6–5.1 0.62 0.73 (NS)
Total bilirubin (mg/dl) 1.01 0.44 0.6–2.22 0.98 0.42 0.6–2.3 0.75 0.11 0.56–0.92 5.25 0.072 (NS)
Direct bilirubin (mg/dl) 0.28 0.26 0.1–0.97 0.26 0.18 0.11–0.92 0.15 0.04 0.1–0.21 7.22 0.027 (S)
  1. KW Kruskal-Wallis test, NS non significant, S significant, HS highly significant