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Table 2 Relative expression of PDX-1, insulin, CYP2J2 genes, and 14, 15-DHET conc. level before and after differentiation of HBM-MSCs to IPCs

From: The expression of cytochrome P4502J2 gene and 14, 15 epoxyeicosatrienoic acid level influence the amount of insulin secreted from human mesenchymal stem cell-derived insulin-producing cells

  Undifferentiated HBM-MSCs Differentiated IPCs P value
PDX-1 1.0 ± 0.03 5.5 ± 0.9 0.046*
Insulin 1.0 ± 0.02 3.0 ± 0.2 0.04*
CYP2J2 1.0 ± 0.37 0.84 ± 0.01 0.31
14-15DHET (pg/mL) 4.85 ± 0.6 3.36 ± 0.4 0.005*
  1. *Statistically significant difference (P value < 0.05)